Dr Dianne E. van der Wal

Dianne van der Wal

Senior Research Fellow 

Product Development and Storage

 

Dr Dianne E. van der Wal is interested in platelet signalling. Her current project focuses on the platelet responses of apheresis platelet donors.  

During her PhD (Utrecht University, the Netherlands), she demonstrated that novel death pathways were triggered in cold-stored platelets as a result of molecular changes in one of the platelet adhesion receptors.

Some patients suffering from bleeding disorder Immune thrombocytopenia (ITP) are unresponsive to current treatments. In her postdoc in Toronto, Canada, she showed that certain antibodies induced removal of sialic acid leading to platelet clearance by liver macrophages. Therefore, desialylation-inhibitors could possibly be used as a novel drug for ITP.
 

Leadership

  • Social media editor for Journal of Thrombosis and Haemostasis 
  • Reviewer for Platelets, EHA Hemashere, ISBT Science Series, Vox Sanguinis and ISBT Congress Abstracts
  • Chairperson ISTH Melbourne 2019
  • Chair of session at ISBT Congress, Nusa Dua, 2015

Awards

  • EHA-ISTH training fellowship 2018
  • THANZ travel award:  HAA 2017
  • Control of Anticoagulation Travel Award and Young Investigator Award: XXIVth Congress of the International Society on Thrombosis and Haemostasis (ISTH), 2013 
  • Abstract Achievement Award: 54th Annual Meeting of American Society of Hematology (ASH), 2012
  • Young Investigator Award:  XXIVth Congress of the International Society on Thrombosis and Haemostasis (ISTH), 2013 

Grants

  • ANZSBT Research funds, 2017: The role of neuraminidases in platelet function in general and during storage.
  • Personal (Post-doctoral) Fellowship (2+1 years; CAD$90,000) from Canadian Lifeblood, Canada, 2011. Unveiling the fundamental differences between anti-GPIbα and anti-GPIIbIIIa-antibody mediated thrombocytopenia: implications for IVIG and alternative therapies.

Teaching and supervison

  • Supervised various research assistants, and Master’s students.
  • Co-supervisor of PhD student.
  • Senior tutor at Monash University, Human Pathology, 3rd year undergraduates.
  • Practical Tutor at Utrecht University, the Netherlands, for various undergraduate courses

 

LinkedIn

Other links:
Google Scholar | ResearchGate | Pubmed | Twitter

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